The Da Vinci Disappearance DLC will start when you reach the “restored memory” location on the map. After each memory you must find another restored memory to continue.
A Roll of the Dice
Find Leonardo’s Assistant, Salai, at the Thieves Guild and bring him back to Leonardo’s Workshop.
Full Sync: Do not drop below 4 health squares.
You should be instantly transported to the thieves guild. Enter to find Salai, but be prepared for a fight! Walk up to the men playing a dice game to start the next cutscene. The fight is after the scene. After that, Salai will run to the next location. The game doesn’t allow you to use a tunnel, so you must ride a horse all the way back into town. You may run into some guards on the way. If the guards are on horse back, lock onto them and steal the horse. Do this five times to unlock an achievement/trophy. The guards may take your horse, allowing you to steal it back again.
Meet back up with Salai and make your way back to Leonardo’s Workshop. Try to avoid any fights to get back to the shop faster. When you reach the shop, a cutscene will automatically play.
Walk to the next restored memory location at the North end of town to enter the next memory.
The One Who Got Away
Infiltrate Belriguardo Palazzo to find Lucrezia Borgia and discover the locations of the stolen Villa paintings.
Full Sync: Do not kill anyone.
This mission requires tons of stealth. If you are even detected, you will lose synchronization. You can read the following guide, or you can view a video on getting past this mission HERE.
Start by jumping to the left into a bail of hay.
Exit the hay and climb the building straight forward. Enter the building via the opening to the right
When inside the building, grab the rope hanging down on the left side. It will swing you left onto some wooden planks. Jump forward, go right, and jump forward again until you reach another hay bail.
Exit the hay bail and run to the other side of the building. Climb up the platform and jump across the wood sticks. Catch the swinging rope to swing right. Enter the next part of the building for a checkpoint.
The next part should be easy enough. Jump across the barrel shelves to the next area. A small bit of dialogue will play among the crowd. Make your way across the top until you jump down into a room. You can find some loot in the dark dead end tunnel. Climb up the wall to the left and jump backwards to a wooden platform to make it to the next area.
You can assassinate some guards up ahead, but if you want full synchronization, don’t do it! Jump down behind the guards and climb up a little box like thing.
You can back jump to some wooden poles to make it to the next area. It’s pretty straight forward.
Eventually, you’ll reach a gate with some greenery on the outside.
Jump to the ruined brick above the gate. Do a back jump to reach the other side. Climb to the right to exit out, then back jump to the garden area. Jump across the fountains in the garden area and walk towards the door to start up another cutscene.
At the end of the cutscene, you’ll need to escape before the time limit runs out. Remember not to kill anyone if you want full synchronization. Run outside and take any short cuts you can. The end will have you performing a leap of faith to the first painting.
The next memory is at the North East end of town. Actually it’s not part of town.
Tail Lucrezia’s old flame, Patrizio, to find the Leonardo painting she gave him in memory of their love.
Full Sync: Do not use the rooftops during the tail.
This should be fairly easy. Follow Patrizio without walking on the rooftops. If others look towards you, or if Partizio looks your direction, hide among groups of people. Don’t forget about the gentle push button when walking. Don’t get too close, but don’t get too far. If you lose sight of your target for 30 seconds, you will have to start over.
When Patrizio walks past some guards, find another route around. The first set of guards will have an alley way to the left. You can kill any guards as long as it’s out of sight from other guards and Patrizio. There were two guards for me in this alleyway. The second set of guards will be next to an alleyway to the right, up some stairs. Patrizio should be headed that direction anyways. The third set will be much tougher. Walk to the left of the guards, down some stairs. Go down the street until you can make a right to the path where Patrizio was walking. He will turn back towards you, so make sure you have an escape route and any crowds to hide in. Follow him until you reach a cutscene.
After the scene you will chase down the man with the painting. You have infinite time, but you must be close to him or the memory will end. You can run on rooftops now, but there are guards on the rooftops. Chase him or cut him off, then kill him. You can also get close enough for a lock on to shoot him. Once you have the painting, leave the Vatican district to end the memory.
The next memory starts at the door of a building South of the last memory.
Recover Leonardo’s Paintings before the merchant sails away with them.
Full Sync: Do not be detected by the robbed disciples.
Run down to the docks for the beginning of this mission, but do not be detected by any of the guards on the way. Either jump from roof to roof stealth-like, or walk within the crowds. Getting caught by the guards on the rooftops does not count against the full sync challenge. At the docks you will find Duccio. Fight him and his gang after a cutscene, but do not kill them. Duccio will run away a few times during the fight to get more friends to help him out. Defeat him and his friends 4 times to find out the location of the other three paintings.
One of the paintings is on a boat not far from your current location. The boat is surrounded by robbed disciples, the ones you’re not supposed to be detected by! There are three off the boat and a lot more on the boat. Use an arrow storm on the men on the boat, but make sure you’re not near the boat or they may come after you. The other men will run off looking for your Assassins. Run on boat and take the painting to end the memory.
The next memory is to the West. Talk to the courtesans to start the memory.
Last Minute Invite
Retrieve the invitation to the art exhibition inside the nobleman’s courtyard without getting caught.
Full Sync: Do not let guards discover any dead bodies inside the restricted area.
Meet up with the courtesans near the dock. They will show you where the invitation is. The invitation is inside a red box in a restricted area. Grab it without being detected. You can assassinate anyone, but make sure their bodies aren’t seen either. Remember, you have the ability to pick up bodies and hide them. The easiest way is to walk around and enter from the North. Hire the courtesans in that area to help you into the restricted area and to distract the guards. Loot the red box and a cutscene will play.
Your next objective is to tackle the courier before he arrives at his destination. Some robbed men will try to get between you and your target. The target will run into the Vatican area. Try and get him before that happens. Run directly to the right along the water area, instead of following him. You should cut him off at the bridge before he reaches the safe zone. Escape and become anonymous to end the memory.
The next memory starts at the bridge. Talk to the courtesans.
The Ezio Auditore Affair
Locate Leonardo’s Paintings at the art exposition and mark them while remaining undetected.
Full Sync: Do not use any type of ranged weaponry
Use your eagle vision to locate the paintings, they will glow yellow. You cannot walk up to them and mark them, however, they are under guard supervision. Use dead bodies to distract everyone. Walk up behind a guard and poison him. Walk away and watch him fall to the ground. The other guards should become distracted, allowing you to mark the first painting. Using courtesans work too. Whatever you do, just make sure you have enough time to mark the painting.
After the first painting, the upper floors will open. Enter the middle circular building, but stay in the crowds. This area is restricted so you must keep hidden. Enter the building and look down the hall. A man will walk back and forth. Poison him and hide while he goes crazy. It’s also possible to assassinate him while hidden with the Cardinals. When it’s possible, walk down the hall to find a room with a hay bale. Climb the wall that’s next to the hay bale to enter the upper floor. Assassinate the guard at the top and drop his body in the hay bale. There will be another guard around the corner. Take a left and you’ll find him at the next left. He will move around so look out. The next guard is at the top of the first set of stairs. He will walk down the hall to the right.
Walk up the last set of stairs out of the dungeon like area, then walk up a set of stairs to the left to earn another checkpoint and find the second painting. There will be a room full of paintings and one guard. Take him out, but not with a ranged weapon! Get close to him to assassinate him, then mark the last painting. Escape the Castello to end the memory. Walk up the stairs and parachute off the top, if you have a parachute. If not, walk back down from the path you came up. The gates will be closed. Instead of going through the gates, climb up some scaffolds on the North Wall. Find an area to jump off the wall into the river to end the memory.
The next memory starts at Leonardo’s Workshop.
Decoding Da Vinci
Piece Leonardo’s hidden drawing back together to discover the entrance to the catacombs containing the Pythagorean temple.
Full Sync: Discover the location of the catacombs in under 5:00
The 5 minute timer starts immediately. Use your eagle vision and find clues on the paintings. The clues will be white markings. Zoom in and click the identify button to confirm the locations. After you found the locations on all the paintings, you must construct the map. You may need to rotate the pieces to fit them in place. You will not have all the pieces. These images are for the paintings and the map:
The next memory is just outside of town to the East, inside a sewer.
The Temple of Pythagoras
Enter the catacombs to find Leonardo and free him from his captors.
Full Sync: Do not lose any health squares.
The first section is a straight shot into the water. You will see a small scene once you hit the water. Climb up to a stone column and move to the right across a crack. Climb up the column to the right and do a back jump. Climb up the stone structure you jumped to and you will see your path. Do a few quick jumps from stone to stone and bar to bar.
At the end of the path will be a cutscene and a fight. This is where you can lose a health square and ruin your chance at full synchronization. Try to attack first and chain all your kills together. If one of them hits you, you could lose a square and your shot at full sync. Don’t forget about counter attacks. If they grab you, try to counter grab. Walk up to Leonardo and assassinate the man that took him.
Your next objective will be to find the final room and secret. Walk down until you reach a giant shrine. Interact with it to drop a huge stone square. Climb up the stone square and climb up the column to the right. Jump to the right of the column to reach the next interactive piece.
Next, jump to the center shrine and make your way around it to find holes going upward. Climb up the holes and do a back jump to the next ledge. Jump straight forward towards the area where the first stone square fell. Make your way around to the next interactive spot as shown in this image:
Enter the newly opened door and make your way downward. After a small scene, climb up the wall opposite the entrance. Do a back jump at the top to reach some wooden planks. Jump from plank to plank to reach a stone face. Jump on the stone face to activate something. Jump to the right next. Move towards a damage stone piece. When you reach this piece, jump to the right. Move down this next area until you see the next stone face. Do a back jump to reach the stone face. From the face, jump to the right onto some stone columns. You will need to do a few quick jumps from one spot to another. Grab a few hanging plants to swing around. The jumps will end next to the face. Jump to the face to open the next door.
Go down to the final room before the center, as Leonardo says. This room has tons of columns. Walk up to the broken down wall near the entrance.
Climb up and jump to the right to interact with a lever. Jump across the platforms and columns to reach the next interactive spot.
Next, jump across a few platforms to the third lever. Then jump across a platform, climb up a column, and jump across a few more platforms to reach the fourth lever.
Make your way down to the bottom for a cutscene that ends the DLC. The ending may vary depending on the completion of the main game.